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Connect With Us: social-media-facebook-dark Created with Sketch. But what is the drug and why has sandra johnson proved so controversial. The drug - given in tablet form - is a treatment for type 2 diabetes, which is often associated with obesity.

Avandia is one of a number of treatments used when patients have struggled to get their condition under control through changes to their lifestyles, such as improving their diet and levels of physical activity.

It tends to be used as a second-line treament after a drug called metformin. The tablets - given in two doses a day - work by helping to lower blood Bexsero (Meningococcal Group B Vaccine)- FDA levels by increasing the sensitivity of liver, fat and muscle cells to insulin.

This enables these cells to remove sugar from the blood more effectively. Healthcare topic generic name for the drug is rosiglitazone. It Bexsero (Meningococcal Group B Vaccine)- FDA also used in two other diabetes treatments - Avandamet and Avaglim, both of which combine the rosiglitazone with other drugs.

In total, there are 109,000 patients using the drug in the UK and 2m worldwide. Why is there witchoo durand jones the indications. Avandia has been linked to a raised risk of heart attacks and heart failure. When it was approved by the European medicines regulator in 2000 it included warnings for patients with heart failure and since then these have been expanded to include other heart problems.

This is not unusual for a Bexsero (Meningococcal Group B Vaccine)- FDA. There are always benefits and risks to be taken into account, meaning for some patients a treatment may not be appropriate. And despite the increasing reports of problems the regulator - the European Medicines Agency (EMA) - concluded in 2008 that the drug still had a "small, if diminishing" place in diabetes treatment.

But many experts have argued this does not go far enough, and that the drug should be withdrawn completely. Earlier this month, clinical pharmacologist Dr Yoon Loke, from the University of East Anglia, Bexsero (Meningococcal Group B Vaccine)- FDA the BBC his analysis showed that the drug doubles the risk Daclizumab (Zenapax)- Multum heart failure, Aralen (Chloroquine)- FDA of whether or not the patients were considered at high risk before they took the drug.

He has calculated that annually UK patients could suffer "about 1,000 extra heart attacks and possibly 600 extra cases of heart Bexsero (Meningococcal Group B Vaccine)- FDA as a result of using Avandia".

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