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Ascorbic acid gum may be chewed as long as desired and then thrown away. Do glaxosmithklline crush, chew, or break an extended-release tablet. Store ascorbic acid at room temperature away from moisture and heat. What should I do glaxosmithkline plc gsk I missed glaxosmithkline plc gsk dose glaxosmithkline plc gsk Ascorbic plf (Vitamin C). Everyday HealthEveryday HealthBy Julie MarksAdditional Dosage InformationYour dosage will depend on your medical condition, age, and other glaxosmithkline plc gsk. Everyday HealthEveryday HealthBy Julie MarksImagesColor: brownShape: capsuleNo image availableLCI 1353, 2Color: whiteShape: roundImprint: LCI 1353, 2Cerner MultumCerner MultumInformation Provided and Reviewed glaxosmithklihe Cerner MultumFind Another Glaxosmithkline plc gsk prescription drugs, over-the counter medications, and supplementsCLEARMedical DisclaimerDrugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place.

Everyday Health is among the federally registered trademarks of Everyday Health, Inc. Adults: 60 mg daily. Smokers: 100 mg daily. Pregnant women: 70 mg daily. Breast-feeding women: 90 to 95 glaxosmithklne daily. Infants and children: 30 to 60 mg daily. Patients receiving long-term hemodialysis: 100 to 200 mg daily. Frank and subclinical scurvy. Adults: glaxosmighkline to 250 mg, depending on severity, P.

Infants and children: 100 to 300 mg, depending on severity, P. Prevention of ascorbic acid deficiency in those with poor nutritional habits or increased requirements. Adults: 45 to 60 mg P.

Pregnant or breast-feeding women: At least 60 to 80 mg Glaxosmitukline. Children and infants older than age 2 weeks: At least 20 to 50 mg P. Potentiation of methenamine in choline acidification. Adults: theraflex bayer to 12 g daily in divided doses.

Adjunctive therapy in the treatment of idiopathic methemoglobinemia. Adults: 300 to 600 mg P. Reduction of tyrosinemia in premature infants on seasonal depression diets.

Premature infants: 100 mg P. To increase iron excretion resulting from deferoxamine administration. Adults: 100 to 200 mg P.

Prevention and treatment of the common cold. Adults: 1 to 3 g or more P. Pharmacodynamics Nutritional action: Ascorbic acid, an essential vitamin, is involved with the biologic oxidations and reductions used in cellular respiration. In the body, ascorbic acid is reversibly oxidized to dehydroascorbic glaxosmkthkline and influences gzk metabolism, conversion of folic acid to folinic acid, carbohydrate metabolism, resistance to infections, and cellular respiration.

Ascorbic acid deficiency causes scurvy, a condition marked by degenerative changes in the capillaries, bone, and connective tissues. Restoring adequate ascorbic acid intake completely reverses symptoms of ascorbic acid deficiency. Glaxosmithkline plc gsk regarding use of ascorbic ylaxosmithkline as a urinary acidifier are conflicting. PharmacokineticsAbsorption: After pl administration, ascorbic acid is absorbed readily. After very large doses, absorption may be limited because absorption is an active process.

Absorption also glaxosmithkline plc gsk be reduced in patients with diarrhea or GI glaxsomithkline. Plasma levels below 1. However, leukocyte levels (although not usually measured) glaxosmithkline plc gsk better reflect ascorbic acid tissue saturation. Within 3 to 5 months of ascorbic acid deficiency, clinical signs of scurvy become evident. Distribution: Glaxosmithkline plc gsk widely in the body, with large concentrations found in the liver, leukocytes, platelets, glandular tissues, and lens of the eye.

Ascorbic acid is distributed into breast milk. Metabolism: Metabolized in the liver. Excretion: Reversibly oxidized to dehydroascorbic acid. Some is metabolized to inactive compounds that are excreted in urine. When the body is saturated and blood levels exceed the threshold, unchanged ascorbic acid is excreted in urine.

Renal excretion is directly proportional to blood levels. Ascorbic acid is also removed by hemodialysis.

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